Description

2-Trifluoromethyl-3-Aminopyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and amino substituents make it an essential intermediate for introducing fluorine-containing motifs, which are pivotal for modulating the physicochemical properties of target molecules. This compound is primarily sought after by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands in transition metal catalysis and organocatalysis.
• Material Science: Building block for synthesizing fluorinated polymers, liquid crystals, and electronic materials that require specific dielectric and surface properties.
• Chemical Research: Versatile reagent in academic and industrial R&D for exploring new fluorination methodologies and heterocyclic chemistry.
• Dye and Pigment Industry: Intermediate for creating specialized fluorinated dyes and pigments with enhanced lightfastness and chemical resistance.

Basic Information

Product Name	2-Trifluoromethyl-3-Aminopyridine
CAS No.	106877-32-1
Molecular Formula	C6H5F3N2
Molecular Weight	162.11 g/mol
Synonyms	3-Amino-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)pyridin-3-amine; 3-Amino-α,α,α-trifluoro-2-picoline; 2-Trifluoromethyl-3-pyridinamine; 3-Pyridinamine, 2-(trifluoromethyl)-; 2-Trifluoromethyl-3-aminopyridine
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-3-Aminopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of amino and fluorinated groups, it is recommended to store under an inert atmosphere for long-term stability and to minimize potential moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.