Description

Felbamate-D4 is a deuterated internal standard specifically designed for the precise quantitative analysis of the antiepileptic drug felbamate in complex biological matrices. This high-purity compound is essential for ensuring accuracy and reliability in mass spectrometry-based methods, such as LC-MS/MS, by correcting for variations in sample preparation and instrument response. It is a critical tool for pharmaceutical research, clinical laboratories, and forensic toxicology professionals engaged in drug metabolism studies, therapeutic drug monitoring, and bioanalytical method development.

Application

• Quantitative Bioanalysis: Serves as a stable isotope-labeled internal standard for the accurate quantification of felbamate in plasma, serum, and other biological fluids using LC-MS/MS.
• Pharmacokinetic & Metabolism Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Therapeutic Drug Monitoring (TDM): Critical for developing and validating robust analytical methods to monitor felbamate concentrations in patient samples for optimal dosing and safety.
• Forensic & Clinical Toxicology: Used in confirmatory testing and method development for the detection of felbamate in cases of overdose or compliance monitoring.
• Reference Standard for Impurity Profiling: Can be utilized as a reference material in the analysis of deuterated impurities or in stability-indicating assay methods.
• Method Development & Validation: Provides a benchmark for establishing specificity, accuracy, precision, and linearity in new analytical procedures.

Basic Information

Product Name	Felbamate-D4
CAS No.	106817-52-1
Molecular Formula	C11H10D4N2O4
Molecular Weight	238.27 g/mol
Synonyms	Felbamate-d4; 2-Phenyl-1,3-propanediol Dicarbamate-d4; 2-Phenyltrimethylene Dicarbamate-d4; W-554-d4; ADD-03055-d4; (±)-2-Phenyl-1,3-propanediol Dicarbamate-d4; 2-Phenyl-1,3-propanediol bis(carbamate)-d4; 1,3-Propanediol, 2-phenyl-, 1,3-dicarbamate-d4
EINECS	Contact for details

Quality Control

Every batch of Felbamate-D4 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive characterization by NMR, MS, and HPLC. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (typically ≥98% by HPLC), isotopic enrichment (≥98 atom % D), and absence of critical impurities. Our quality commitment supports compliance with GLP and ISO standards for research and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 98%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.