Description

Tin Mesoporphyrin CAS NO 106344-20-1 is a synthetic metalloporphyrin complex where tin is coordinated within a mesoporphyrin IX framework. This compound is a potent and selective inhibitor of heme oxygenase, a critical enzyme in the heme degradation pathway. It is primarily utilized in biochemical and pharmaceutical research for studying oxidative stress, cellular protection mechanisms, and as a potential therapeutic agent. Industries engaged in advanced life science research, drug discovery, and diagnostic development are the key users of this high-purity biochemical.

Application

• Heme Oxygenase (HO) Inhibition Studies: A standard research tool for investigating the HO-1 and HO-2 enzyme pathways in cellular and animal models.
• Oxidative Stress & Cytoprotection Research: Used to modulate cellular defense mechanisms against oxidative damage in neuroscience, cardiology, and hepatology research.
• Therapeutic Agent Development: Investigated for potential applications in treating hyperbilirubinemia (jaundice), ischemia-reperfusion injury, and inflammatory conditions.
• Biochemical Reference Standard: Serves as a high-purity calibrant and control in analytical method development for porphyrin analysis.
• Photodynamic Therapy (PDT) Research: Explored for its photosensitizing properties in preclinical studies for cancer treatment.
• Enzyme Mechanism & Kinetics: Employed in detailed enzymatic studies to understand inhibition constants and binding interactions.

Basic Information

Product Name	Tin Mesoporphyrin
CAS No.	106344-20-1
Molecular Formula	C34H36N4O4Sn
Molecular Weight	683.37 g/mol
Synonyms	SnMP; Tin(IV) Mesoporphyrin IX Dichloride; Stannsoporphyrin; Tin Mesoporphyrin IX; Tin Protoporphyrin Dichloride (related analog); HO Inhibitor; Heme Oxygenase Inhibitor; 5,10,15,20-Tetrakis(2,4,6-trimethylphenyl)porphyrinato tin(IV) dichloride (common structural analog name)
EINECS	Contact for details

Quality Control

Our Tin Mesoporphyrin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and mass spectrometry for structural confirmation, and elemental analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research-grade specifications. We support cGMP standards for advanced material production where required.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided. Keep the container in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	Dark purple to brown crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Research Grade)
Purity (HPLC)	≥ 98% (High-Purity Grade)
Solubility	Soluble in DMSO, DMF; sparingly soluble in organic solvents
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.