Description

D-Glucose-2-C-D is a stable isotope-labeled analog of D-glucose, specifically labeled with carbon-13 at the C-2 position. This compound is an essential tool for advanced metabolic research and analytical method development, providing a non-radioactive tracer for precise pathway analysis. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic sectors for applications requiring high isotopic purity and chemical stability.

Application

• Metabolic Flux Analysis (MFA): Used as a 13C tracer to study glucose metabolism, glycolysis, and the pentose phosphate pathway in cell cultures and biological systems.
• Internal Standard for Mass Spectrometry: Serves as a critical internal standard in LC-MS and GC-MS workflows for the accurate quantification of glucose and related metabolites in complex biological matrices.
• NMR Spectroscopy: Employed in 13C-NMR studies to investigate enzymatic mechanisms and metabolic pathways without spectral interference.
• Pharmaceutical R&D: Facilitates drug metabolism and pharmacokinetics (DMPK) studies to trace the metabolic fate of new chemical entities.
• Diagnostic Assay Development: Used in the calibration and validation of clinical diagnostic kits for measuring glucose metabolism disorders.
• Biochemical Research: A key reagent for in vitro enzyme assays and studies of carbohydrate-active enzymes.

Basic Information

Product Name	D-Glucose-2-C-D
CAS No.	106032-60-4
Molecular Formula	C6H11DO6 *
Molecular Weight	181.16 g/mol (for C6H11DO6)
Synonyms	D-Glucose-2-13C; [2-13C]-D-Glucose; 2-13C-Labeled D-Glucose; D-Glucose (2-13C); (2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal-2-13C; Deuterated D-Glucose-2-13C; Stable Isotope-Labeled Glucose; 13C-Glucose Tracer
EINECS	Contact for details

* Note: The formula indicates deuteration (D) at an unspecified position alongside 13C labeling at C-2. The exact structure should be confirmed via the technical data sheet.

Quality Control

Our D-Glucose-2-C-D is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and isotopic purity, meeting the exacting standards required for research and diagnostic applications. Certificates of Analysis (COA) are provided, detailing specifications for isotopic enrichment, chemical purity (by HPLC), and identity confirmation (by NMR/MS).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR/NMR)	Conforms to structure
Isotopic Enrichment (13C at C-2)	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98.0%
Deuterium Content (NMR/MS)	As per COA
Specific Optical Rotation	+52.5° to +53.0° (c=10 in H2O)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.