Description

D-Glucose-2-13C is a stable isotope-labeled analog of D-glucose, specifically enriched with carbon-13 at the C-2 position. This high-purity labeled compound is essential for advanced metabolic research, enabling precise tracking and quantification of glucose utilization and metabolic flux in biological systems. It is a critical reagent for scientists and manufacturers in pharmaceutical R&D, clinical diagnostics, and academic research focused on metabolism, diabetes, and cancer biology.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to map intracellular metabolic pathways and quantify reaction rates in cell cultures and tissues.
• Pharmaceutical Research & Development: Employed in drug discovery to study the effects of new compounds on glucose metabolism and energy homeostasis.
• Clinical Diagnostic Assays: Serves as an internal standard in mass spectrometry-based methods for the accurate measurement of glucose and related metabolites in biological fluids.
• Nutritional and Metabolic Studies: Facilitates research into carbohydrate metabolism, insulin resistance, and metabolic disorders like diabetes and obesity.
• Biotechnology and Fermentation Monitoring: Applied to analyze and optimize substrate utilization and product yield in microbial and cell culture processes.
• Isotope Dilution Mass Spectrometry (IDMS): A key component for achieving high accuracy and precision in quantitative analytical methods.

Basic Information

Product Name	D-Glucose-2-13C
CAS No.	105931-74-6
Molecular Formula	C513CH12O6
Molecular Weight	181.15 g/mol
Synonyms	D-(+)-Glucose-2-13C; Dextrose-2-13C; (2-13C)-D-Glucose; D-Glucose (2-13C); 2-13C-Labeled D-Glucose; 13C-Glucose; Glucose-2-13C; α-D-Glucopyranose-2-13C
EINECS	Contact for details

Quality Control

Every batch of D-Glucose-2-13C is manufactured and tested under strict quality management systems to ensure exceptional isotopic and chemical purity, critical for sensitive research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical methods (NMR, HPLC, MS) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term stability, consider storage under inert atmosphere or in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C (at C-2)
Chemical Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	+52.5° to +53.0° (c=10 in H2O)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.