Description

2-Phenoxy-5-(Trifluoromethyl)Pyridine is a high-purity, multi-functional heterocyclic building block. This compound is valued for its unique trifluoromethyl and phenoxy substituents, which impart desirable physicochemical properties for advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients. Its structural features make it a critical intermediate in medicinal chemistry and crop protection product development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorine-containing structure.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging agent in the design of chemical probes and enzyme inhibitors for biological pathway studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Phenoxy-5-(Trifluoromethyl)Pyridine
CAS No.	105626-77-5
Molecular Formula	C12H8F3NO
Molecular Weight	239.19 g/mol
Synonyms	5-(Trifluoromethyl)-2-phenoxypyridine; 2-Phenoxy-5-(trifluoromethyl)pyridine; Pyridine, 2-phenoxy-5-(trifluoromethyl)-; 2-Phenoxy-α,α,α-trifluoro-p-toluidine (obsolete); 2-(Phenoxy)-5-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Phenoxy-5-(Trifluoromethyl)Pyridine is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure compliance with industry standards and customer-specific requirements. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.