Description

7-Epitaxol is a high-purity, specialized taxane derivative with the CAS registry number 105454-04-4. This compound serves as a critical advanced intermediate in the synthesis of complex pharmaceutical agents, particularly in oncology research and development. It is essential for pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the production of next-generation chemotherapeutic drugs and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent taxane-based anticancer drugs, such as paclitaxel and docetaxel analogs.
• Oncology Research: Used as a reference standard and a precursor in biochemical research to study structure-activity relationships (SAR) and develop new therapeutic candidates.
• Process Chemistry: Employed in process development and scale-up activities for the commercial manufacturing of complex active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Utilized in organic synthesis laboratories for the preparation of novel diterpenoid derivatives with potential biological activity.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method development in pharmaceutical analysis.

Basic Information

Product Name	7-Epitaxol
CAS No.	105454-04-4
Molecular Formula	C47H51NO14
Molecular Weight	853.91 g/mol
Synonyms	7-Epi-taxol; 7-Epimer of Paclitaxel; 7-Epimeric Paclitaxel; 7-Epitaxol A; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecah-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl benzoate; 7-Epi Paclitaxel; 7-Epimer Taxol
EINECS	Contact for details

Quality Control

Our 7-Epitaxol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identification by NMR and mass spectrometry. We provide full traceability and detailed Certificates of Analysis (COA) to support your regulatory and research requirements, ensuring compliance with cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, ideally between 15-25°C (59-77°F), in a dry environment. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Optical Rotation	Contact for details
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.