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δ-17-Tetranorprostaglandin E1 CAS NO 105450-12-2


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CAS No.:105450-12-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

δ-17-Tetranorprostaglandin E1 is a synthetic prostaglandin analog, a key intermediate in the synthesis of advanced pharmaceutical compounds. This compound matters for its role in developing therapeutic agents that target specific physiological pathways, offering high purity and structural precision for research and manufacturing. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in prostaglandin-related drug discovery and development.

Application

  • Pharmaceutical Intermediate: A critical building block in the synthesis of prostaglandin-based drugs and active pharmaceutical ingredients (APIs).
  • Biochemical Research: Used as a reference standard and tool compound in pharmacological studies to investigate prostaglandin receptor activity and signaling pathways.
  • Fine Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex, structurally modified prostaglandin analogs.
  • Drug Discovery Programs: Employed in high-throughput screening and lead optimization for developing new therapeutics targeting inflammation, cardiovascular function, and ocular pressure.
  • Academic Research: Utilized in university and institutional labs for fundamental studies on eicosanoid biology and medicinal chemistry.

Basic Information

Product Name δ-17-Tetranorprostaglandin E1
CAS No. 105450-12-2
Molecular Formula C18H28O5
Molecular Weight 324.41 g/mol
Synonyms δ-17-Tetranor PGE1; 13,14-Dihydro-15-keto-δ-17-tetranor PGE1; 11α,15α-Dihydroxy-9-oxo-δ-17-tetranorprosta-5,13-dien-1-oic Acid; 15-Keto-δ-17-tetranor PGE1; 15-Keto-13,14-dihydro-δ-17-tetranor PGE1; δ-17-Tetranor-15-keto-13,14-dihydro-PGE1; 9-Oxo-11α,15α-dihydroxy-δ-17-tetranorprosta-5,13-dien-1-oic Acid
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Quality Control

Our δ-17-Tetranorprostaglandin E1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Any single impurity ≤ 0.5%
Residual Solvents (GC) Complies with ICH guidelines
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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