Description

Decarboxy Ciprofloxacin CAS NO 105394-83-0 is a key pharmaceutical intermediate and a structural analog of the widely used fluoroquinolone antibiotic, ciprofloxacin. This compound is of significant importance in the research and development of novel antibacterial agents and for studying structure-activity relationships. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and antibiotic synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of ciprofloxacin analogs and next-generation fluoroquinolone antibiotics.
• Medicinal Chemistry Research: Used as a reference standard and precursor in studies aimed at modifying the quinolone core to enhance antibacterial activity or reduce resistance.
• Active Pharmaceutical Ingredient (API) Development: Serves as a key starting material (KSM) or advanced intermediate in the multi-step synthesis of complex API molecules.
• Biochemical Research: Employed in microbiological and enzymatic studies to investigate the mechanism of action of topoisomerase inhibitors.
• Quality Control & Analytical Standards: Utilized as a high-purity reference compound in HPLC, LC-MS, and NMR for the identification and quantification of related substances in API batches.

Basic Information

Product Name	Decarboxy Ciprofloxacin
CAS No.	105394-83-0
Molecular Formula	C16H19FN4O2
Molecular Weight	318.35 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid decarboxylated; 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid decarboxylated derivative; Ciprofloxacin Decarboxylated; Ciprofloxacin Impurity; CPDX; 1-Cyclopropyl-6-fluoro-7-(piperazin-1-yl)quinolin-4(1H)-one
EINECS	Contact for details

Quality Control

Our Decarboxy Ciprofloxacin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-grade standards suitable for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.