Description

Triacsin A CAS NO 105201-46-5 is a potent and selective inhibitor of long-chain acyl-CoA synthetase (ACSL), a key enzyme in lipid metabolism. This compound is a critical research tool for studying fatty acid metabolism, lipid droplet formation, and related metabolic disorders. It is essential for researchers and developers in the fields of biochemistry, metabolic disease research, and pharmaceutical development.

Application

• Biochemical Research: Used as a selective inhibitor to study the role of long-chain acyl-CoA synthetases in cellular lipid metabolism.
• Metabolic Disease Studies: A key tool for investigating the pathogenesis of conditions like obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD).
• Lipid Droplet Biology: Employed to probe the mechanisms of lipid storage and mobilization within cells.
• Drug Discovery: Serves as a reference compound and pharmacological probe in the development of novel therapeutics targeting metabolic pathways.
• Cell Signaling Research: Used to elucidate the connections between lipid metabolism and various cellular signaling cascades.
• Academic & Institutional Laboratories: A standard reagent for graduate and post-doctoral research in life sciences.

Basic Information

Product Name	Triacsin A
CAS No.	105201-46-5
Molecular Formula	C₂₀H₂₅N₃O₂
Molecular Weight	339.43 g/mol
Synonyms	Triacsin A; 2-Heptyl-4-hydroxyquinoline-3-carboxanilide; 2-Heptyl-4-hydroxyquinoline-3-carboxylic acid anilide; 2-Heptyl-4-hydroxy-3-quinolinecarboxanilide; NSC 332889; ACSL Inhibitor; Long-chain acyl-CoA synthetase inhibitor
EINECS	Contact for details

Quality Control

Our Triacsin A is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.