Description

Bryostatin B is a potent, naturally occurring macrocyclic lactone belonging to the bryostatin family of compounds. This high-value molecule is of significant interest in advanced biomedical research due to its unique mechanism of action as a modulator of protein kinase C (PKC). It is primarily sought after by pharmaceutical R&D teams, academic research institutions, and biotechnology companies engaged in the development of novel therapeutic agents.

Application

• Biomedical Research: A critical tool for studying protein kinase C (PKC) signaling pathways, cellular differentiation, and immune cell modulation.
• Oncology Research: Investigated for its potential anti-cancer properties, including the ability to induce apoptosis and inhibit tumor growth in preclinical models.
• Neuroscience Studies: Explored for neuroprotective and memory-enhancing effects, with research applications in Alzheimer's disease and other cognitive disorders.
• Immunology & Virology: Used in studies examining latency reversal in HIV and other viral infections, as well as for modulating immune responses.
• Drug Discovery & Development: Serves as a lead compound or pharmacophore model for the synthesis of novel analogs with improved pharmacological profiles.
• Biochemical Assays: Employed as a standard or reference material in high-throughput screening and biochemical assays targeting PKC.

Basic Information

Product Name	Bryostatin B
CAS No.	104841-30-7
Molecular Formula	C45H68O17
Molecular Weight	881.0 g/mol
Synonyms	Bryostatin B; NSC 339555; Bryostatin-2; (1S,3S,4S,5R,7S,10S,11S,12S,14E,16R,19S,20R,21S)-20-[(2S,3S,4R)-3,4-Dihydroxy-2-methyltetrahydro-2H-pyran-4-yl]-5,7,10,11,19-pentahydroxy-3,11-dimethyl-9-oxo-8-oxatetracyclo[10.10.0.0²,¹⁰.0⁴,⁸]docosa-14,16-diene-12,21-diyl diacetate
EINECS	Contact for details

Quality Control

Our Bryostatin B is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider storage under an inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.