Description

2-Bromo-3-Fluorobenzotrifluoride is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents on a trifluoromethylated benzene ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine atoms enhance biological activity and stability.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing properties.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Stille, Negishi couplings) to form biaryl structures.
• Fluorination Chemistry: Used as a standard or reagent in studies exploring new fluorination methodologies and the effects of fluorine substitution.
• Chemical Reference Standard: Employed in analytical laboratories as a pure standard for method development and quality control in related chemical processes.

Basic Information

Product Name	2-Bromo-3-Fluorobenzotrifluoride
CAS No.	104540-42-3
Molecular Formula	C7H3BrF4
Molecular Weight	242.99 g/mol
Synonyms	1-Bromo-2-fluoro-3-(trifluoromethyl)benzene; 2-Fluoro-3-(trifluoromethyl)bromobenzene; 3-Fluoro-2-(trifluoromethyl)bromobenzene; 2-Bromo-α,α,α-trifluoro-3-fluorotoluene; Benzene, 1-bromo-2-fluoro-3-(trifluoromethyl)-; 3-(Trifluoromethyl)-2-fluorobromobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluorobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for fine chemical intermediates in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.