Description

Ethyl 4,6-Dihydroxy-2-(Trifluoromethyl)Nicotinate is a high-value trifluoromethylated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic incorporation of the trifluoromethyl group, which is essential for modulating the physicochemical properties of target molecules, enhancing metabolic stability and lipophilicity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group improves biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty chemicals, ligands, or functional materials with unique electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Ethyl 4,6-Dihydroxy-2-(Trifluoromethyl)Nicotinate
CAS No.	103900-77-2
Molecular Formula	C9H8F3NO4
Molecular Weight	251.16 g/mol
Synonyms	Ethyl 4,6-dihydroxy-2-(trifluoromethyl)pyridine-3-carboxylate; 2-(Trifluoromethyl)-4,6-dihydroxynicotinic Acid Ethyl Ester; 4,6-Dihydroxy-2-(trifluoromethyl)nicotinic Acid Ethyl Ester; 3-Carbethoxy-4,6-dihydroxy-2-trifluoromethylpyridine; Ethyl 4,6-dihydroxy-2-trifluoromethylnicotinate; 103900-77-2; Nicotinic acid, 4,6-dihydroxy-2-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4,6-Dihydroxy-2-(Trifluoromethyl)Nicotinate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.