Description

2-Chloro-6-Fluorobenzotrifluoride 98 is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate for introducing the trifluoromethyl and halogenated phenyl motifs, which are critical for modulating the physicochemical properties of target molecules. It is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and CNS-targeting drugs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances bioavailability and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies.
• Functional Material Development: Building block for polymers and advanced materials requiring specific dielectric or surface properties.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to create complex biaryl structures.
• Organic Synthesis Research: Used in academic and industrial labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	2-Chloro-6-Fluorobenzotrifluoride 98
CAS No.	103889-37-8
Molecular Formula	C7H3ClF4
Molecular Weight	198.55 g/mol
Synonyms	1-Chloro-3-fluoro-2-(trifluoromethyl)benzene; 2-Chloro-α,α,α,6-tetrafluorotoluene; 2-Chloro-6-fluorobenzyl trifluoride; 2-Chloro-6-fluorotrifluoromethylbenzene; 2-Chloro-α,α,α,6-tetrafluorotoluene; 3-Fluoro-2-(trifluoromethyl)chlorobenzene; Benzene, 1-chloro-3-fluoro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluorobenzotrifluoride 98 is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure the ≥98% purity specification and identity are met. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.