Description

5-Azidoalrestatin is a specialized azido-functionalized derivative of alrestatin, designed for advanced research and development applications. This compound serves as a critical building block and a versatile chemical probe in the synthesis of novel bioactive molecules and pharmaceutical intermediates. It is primarily utilized by researchers and development teams in the pharmaceutical, biotechnology, and agrochemical sectors for targeted drug discovery and chemical biology studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting diabetic complications.
• Chemical Biology Probe: Used to study enzyme inhibition mechanisms and protein interactions, leveraging the reactive azido group for labeling or conjugation.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop new classes of aldose reductase inhibitors.
• Bioconjugation: The azido group enables efficient click chemistry reactions for attaching fluorescent tags, affinity labels, or other functional moieties to biomolecules.
• Agrochemical Development: Investigated as a potential intermediate for creating new crop protection agents with specific modes of action.
• Academic Research: Serves as a valuable tool in university and institutional labs for fundamental studies in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	5-Azidoalrestatin
CAS No.	103884-86-2
Molecular Formula	C16H12N4O3
Molecular Weight	308.29 g/mol
Synonyms	5-Azido-3-[(4-bromo-2-fluorophenyl)methyl]-4-oxo-2-thioxo-1,3-thiazolidineacetic Acid; 5-Azidoalrestatin; Alrestatin Azido Derivative; 5-Azido-3-[(4-bromo-2-fluorobenzyl)]-4-oxo-2-thioxothiazolidine-4-acetic Acid; 5-Azido-3-(4-bromo-2-fluorobenzyl)-4-oxo-2-thioxo-1,3-thiazolidine-4-acetic Acid; 5-Azido-3-(4-bromo-2-fluorobenzyl)-2-thioxo-4-thiazolidinoneacetic Acid; AZD-Alrestatin
EINECS	Contact for details

Quality Control

Our 5-Azidoalrestatin is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.