Description

2-Aminoethoxy-[(2R)-2-[(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-Tetraenoyl]Oxy-3-[(Z)-Octadec-1-Enoxy]Propoxy]Phosphinic Acid is a high-purity, structurally defined phospholipid derivative of significant interest in advanced biochemical research and development. This compound matters for its role as a key synthetic intermediate and functional component in the study of membrane biophysics, lipid signaling, and targeted drug delivery systems. It is primarily needed by research institutions and pharmaceutical companies engaged in developing novel lipid-based therapeutics, liposomal formulations, and diagnostic agents.

Application

• Pharmaceutical Research & Development: As a critical intermediate in the synthesis of novel phospholipid-based active pharmaceutical ingredients (APIs) and prodrugs.
• Liposome & Nanoparticle Formulation: For the development of advanced drug delivery vehicles, including stealth liposomes and lipid nanoparticles (LNPs) for mRNA and gene therapy applications.
• Biochemical & Cell Biology Studies: As a tool compound for investigating lipid metabolism, membrane protein interactions, and intracellular signaling pathways.
• Diagnostic Agent Development: In the creation of contrast agents or labeled probes for medical imaging techniques.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biomimetic Membrane Systems: Used in the fabrication of artificial membranes and biosensors to study membrane fluidity and permeability.

Basic Information

Item	Details
Product Name	2-Aminoethoxy-[(2R)-2-[(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-Tetraenoyl]Oxy-3-[(Z)-Octadec-1-Enoxy]Propoxy]Phosphinic Acid
CAS No.	103597-60-0
Molecular Formula	C43H78NO8P
Molecular Weight	768.05 g/mol
Synonyms	1-Oleoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine-N-(2-aminoethyl) phosphonate; AAPE; Aminoethylphosphonate derivative of PAPE; 1-(1Z-Octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine-N-(2-aminoethyl) phosphonate; Phospholipid 103597-60-0; sn-Glycero-3-phosphoethanolamine-N-(2-aminoethyl) phosphonate derivative; (2R)-2-[(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoyl]oxy-3-[(Z)-octadec-9-enoxy]propyl 2-aminoethyl hydrogen phosphate
EINECS	Contact for details

Quality Control

Our 2-Aminoethoxy-[(2R)-2-[(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-Tetraenoyl]Oxy-3-[(Z)-Octadec-1-Enoxy]Propoxy]Phosphinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific research or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and light-sensitive nature. For long-term storage, desiccate. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.