Description

Ethyl 3-(Chlorosulfonyl)Propanoate is a versatile and reactive organic sulfonyl chloride ester, serving as a critical building block in advanced chemical synthesis. Its bifunctional nature, featuring both an ester and a highly electrophilic sulfonyl chloride group, makes it invaluable for constructing complex molecular architectures. This intermediate is primarily sought after by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of sulfonamides, sulfonate esters, and other functionalized compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sulfonamide pharmacophores which are prevalent in drugs for hypertension, antibacterial, and anticancer therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the sulfonyl moiety can enhance biological activity and selectivity.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers with specific thermal, mechanical, or surface properties.
• Organic Synthesis Reagent: Employed in research laboratories for the preparation of sulfonate esters and as a sulfonylating agent in multi-step synthetic routes.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of sulfonated dyes and colorants, improving solubility and fastness properties.

Basic Information

Product Name	Ethyl 3-(Chlorosulfonyl)Propanoate
CAS No.	103472-25-9
Molecular Formula	C5H9ClO4S
Molecular Weight	200.64 g/mol
Synonyms	3-(Chlorosulfonyl)propanoic Acid Ethyl Ester; Ethyl 3-Chlorosulfonylpropionate; Propanoic acid, 3-(chlorosulfonyl)-, ethyl ester; Ethyl β-(Chlorosulfonyl)propionate; NSC 405124; 103472-25-9
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Chlorosulfonyl)Propanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong bases and nucleophiles; keep away from incompatible materials such as amines, alcohols, and strong oxidizers. Use under an inert atmosphere for prolonged storage to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.