Description

1,3-Dideaza-9-(2-Hydroxy-3-Nonyl)Adenine is a synthetic purine nucleoside analog with a unique structural modification, offering significant research potential in biochemical pathways. This compound is valued for its role as a potent and selective inhibitor of S-adenosylhomocysteine hydrolase (SAH hydrolase), a key enzyme in cellular methylation processes. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for investigating antiviral mechanisms, epigenetic regulation, and as a lead compound in drug discovery programs.

Application

• Biochemical Research: As a tool compound for studying SAH hydrolase inhibition and its effects on viral replication and cellular methylation.
• Antiviral Agent Development: Serves as a reference standard and a potential scaffold for developing novel antiviral therapeutics.
• Epigenetics Studies: Used to investigate the role of methylation in gene expression and regulation due to its impact on methyltransferase activity.
• Pharmaceutical Intermediates: Acts as a key synthetic intermediate in the preparation of more complex nucleoside-based active pharmaceutical ingredients (APIs).
• Enzyme Kinetics: Employed in in vitro assays to determine enzyme kinetics and inhibition constants for SAH hydrolase.

Basic Information

Product Name	1,3-Dideaza-9-(2-Hydroxy-3-Nonyl)Adenine
CAS No.	103298-52-8
Molecular Formula	C₁₇H₂₇N₅O₂
Molecular Weight	333.43 g/mol
Synonyms	9-(2-Hydroxy-3-nonyl)-1,3-dideazaadenine; 1,3-Dideazaadenosine Derivative; SAH Hydrolase Inhibitor; 9-(2-Hydroxy-3-nonyl)adenine analog; DZNep precursor; 3-Deazaneplanocin A related compound; Nucleoside analog inhibitor; 103298-52-8
EINECS	Contact for details

Quality Control

Our 1,3-Dideaza-9-(2-Hydroxy-3-Nonyl)Adenine is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. All products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.