Description

19-Hydroxyaldosterone is a significant steroid metabolite and a key intermediate in the biosynthesis and metabolic pathways of aldosterone. This compound is of critical importance for research into the renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure and electrolyte balance. It is primarily utilized by pharmaceutical R&D laboratories, clinical research organizations, and academic institutions focused on endocrinology, hypertension, and cardiovascular disease studies.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for the quantification and qualification of aldosterone and related metabolites in biological samples via LC-MS/MS or HPLC.
• Biochemical Research: Essential for in-vitro and in-vivo studies investigating the biosynthesis, metabolism, and physiological effects of mineralocorticoids.
• Diagnostic Kit Development: Serves as a critical raw material in the development and calibration of immunoassays and ELISA kits for hormonal disorder diagnostics.
• Metabolite Profiling: Used in metabolomics research to understand disease states related to adrenal gland function and steroid hormone imbalances.
• Drug Discovery & Development: Acts as a key intermediate or target molecule in the development of novel therapeutics for conditions like primary aldosteronism and resistant hypertension.

Basic Information

Item	Details
Product Name	19-Hydroxyaldosterone
CAS No.	103246-10-2
Molecular Formula	C21H30O6
Molecular Weight	378.46 g/mol
Synonyms	19-Hydroxyaldosterone; 11β,21-Dihydroxy-3,20-dioxopregn-4-en-18-al; 19-Hydroxy-aldosterone; Aldosterone, 19-hydroxy-; 18,11-Hemiacetal of 11β,19,21-trihydroxy-3,20-dioxopregn-4-en-18-al
EINECS	Contact for details

Quality Control

Every batch of 19-Hydroxyaldosterone is manufactured and tested under strict quality management systems. We guarantee high chemical purity and identity confirmed by advanced analytical techniques. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, purity, and identification. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical research and diagnostic development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.