Description

Hepoxilin B4 CAS NO 103188-12-1 is a specialized epoxy-hydroxy eicosanoid derivative, a biologically active metabolite of arachidonic acid. This compound is of significant interest in biochemical and pharmacological research due to its role as a lipid mediator. It is primarily utilized by research institutions and pharmaceutical development teams investigating inflammatory pathways, cellular signaling, and novel therapeutic targets.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of eicosanoid metabolism and lipid signaling cascades.
• Pharmacological Studies: Investigation of its effects on inflammation, ion transport, and cellular communication for potential drug discovery.
• Cell Biology: Exploration of its role in intracellular signaling mechanisms and receptor interactions.
• Analytical Standard: Serves as a high-purity calibrant for analytical methods like LC-MS and HPLC in metabolomics and lipidomics.
• Enzyme Substrate/Inhibitor Research: Used to study the activity of epoxide hydrolases and related enzymes.

Basic Information

Product Name	Hepoxilin B4
CAS No.	103188-12-1
Molecular Formula	C20H32O4
Molecular Weight	336.47 g/mol
Synonyms	HXB4; (8R,9S,10S,11Z,14Z)-8,9-Epoxy-10-hydroxy-11,14-icosadienoic Acid; 10-Hydroxy-8,9-epoxy-5Z,11Z,14Z-eicosatrienoic Acid; 10(S)-Hydroxy-8(R),9(S)-epoxy-5Z,11Z,14Z-eicosatrienoic Acid; HXB4; Hepoxilin B4
EINECS	Contact for details

Quality Control

Our Hepoxilin B4 is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum matches reference
Purity (HPLC)	≥ 95% (Area Percent)
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.