Description

1,2-Dibromoethane-1-Sulfonyl Fluoride is a specialized organobromine and sulfonyl fluoride building block of significant interest in advanced synthetic chemistry. Its unique bifunctional structure, featuring both a reactive sulfonyl fluoride group and bromoalkyl substituents, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of sulfonamide-based drug candidates, particularly for targeted covalent inhibitors.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides that leverage its reactive handles for selective bioactivity.
• Chemical Biology Probe Development: Acts as an electrophilic warhead in activity-based protein profiling (ABPP) to label and study enzyme active sites.
• Polymer & Material Science: Employed as a cross-linking agent or functional monomer to introduce sulfonyl fluoride moieties into polymers for advanced material properties.
• Organic Synthesis Building Block: Facilitates SuFEx (Sulfur Fluoride Exchange) click chemistry and various nucleophilic substitution reactions to create diverse chemical libraries.

Basic Information

Product Name	1,2-Dibromoethane-1-Sulfonyl Fluoride
CAS No.	103020-97-9
Molecular Formula	C2H3Br2FO2S
Molecular Weight	285.91 g/mol
Synonyms	1,2-Dibromoethanesulfonyl Fluoride; Ethanesulfonyl Fluoride, 1,2-dibromo-; 1,2-Dibromoethylsulfonyl Fluoride; 2-Bromo-1-(fluorosulfonyl)ethyl Bromide; NSC 405124; Dibromoethanesulfonyl Fluoride
EINECS	Contact for details

Quality Control

Our production of 1,2-Dibromoethane-1-Sulfonyl Fluoride adheres to stringent quality management protocols. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and GC to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and highly volatile compound, keep away from heat, sparks, and open flame. Ensure containers are kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.