Description

4-(Trifluoromethyl)-1H-Imidazole-2-Carbaldehyde is a high-value trifluoromethylated heterocyclic building block essential for advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of the trifluoromethyl group significantly alters biological activity and metabolic stability. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a precursor for functionalized ligands and monomers in the creation of specialty polymers and advanced materials.
• Chemical Research: A versatile building block in medicinal chemistry and process R&D for structure-activity relationship (SAR) studies.
• Fluorine Chemistry: An important reagent for introducing the pharmacologically privileged trifluoromethyl group into heterocyclic scaffolds.

Basic Information

Product Name	4-(Trifluoromethyl)-1H-Imidazole-2-Carbaldehyde
CAS No.	102808-02-6
Molecular Formula	C5H3F3N2O
Molecular Weight	164.09 g/mol
Synonyms	2-Formyl-4-(trifluoromethyl)-1H-imidazole; 4-(Trifluoromethyl)-1H-imidazole-2-carboxaldehyde; 1H-Imidazole-2-carboxaldehyde, 4-(trifluoromethyl)-; 4-Trifluoromethyl-1H-imidazole-2-carbaldehyde; 2-Aldehyde-4-trifluoromethylimidazole; 4-(Trifluoromethyl)imidazole-2-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-(Trifluoromethyl)-1H-Imidazole-2-Carbaldehyde is manufactured and tested under strict quality management systems. We ensure compliance with relevant industry standards, and comprehensive analytical data, including HPLC, NMR, and mass spectrometry, is documented. A Certificate of Analysis (COA) is provided with each shipment to guarantee identity, purity, and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.