Description

11-Deoxy-11,12-Methanoprostaglandin E2 is a synthetic prostaglandin analog, a key intermediate in the research and development of novel pharmaceutical compounds. Its modified structure provides enhanced metabolic stability, making it a valuable tool for studying prostaglandin receptor activity and signaling pathways. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutics for inflammation, pain management, and reproductive health.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of advanced prostaglandin-based drug candidates.
• Biochemical Research: Used as a reference standard and probe in studies of prostaglandin E2 (PGE2) receptor subtypes (EP1-EP4) and their physiological roles.
• Inflammation & Immunology Studies: Employed in preclinical research to investigate pathways related to pain, fever, and inflammatory responses.
• Reproductive Health Research: Applied in studies focusing on uterine contractility and cervical ripening mechanisms.
• Chemical Synthesis: Acts as a sophisticated building block for the preparation of more complex, biologically active prostaglandin derivatives.

Basic Information

Product Name	11-Deoxy-11,12-Methanoprostaglandin E2
CAS No.	102769-45-9
Molecular Formula	C₂₁H₃₄O₅
Molecular Weight	366.49 g/mol
Synonyms	11-Deoxy-11,12-methano-PGE2; 11,12-Methanoprostaglandin E2, 11-deoxy-; 9-Oxo-11-deoxy-11,12-methanoprosta-5,13-dien-1-oic acid; 11-Deoxy-11,12-methano-PGE₂; (5Z,13E)-(9S,11R,15S)-9,15-Dihydroxy-11-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-10,10-dimethyl-3-oxatricyclo[7.2.1.0²,⁷]dodec-5-ene-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 11-Deoxy-11,12-Methanoprostaglandin E2 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.