Description

3,7-Dihydro-1,3-Dipropyl-7-(2-Propynyl)-1H-Purine-2,6-Dione is a high-purity xanthine derivative, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its role as a versatile building block in the synthesis of novel adenosine receptor antagonists and other bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents for neurological and cardiovascular applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potent and selective adenosine A1 and A2A receptor antagonists.
• Neurological Research: Used in the development of potential therapeutic agents for conditions such as Parkinson's disease, neuropathic pain, and cognitive disorders.
• Cardiovascular Research: Employed in creating compounds under investigation for heart failure, arrhythmias, and renal protection.
• Chemical Biology: Serves as a molecular probe to study adenosine receptor signaling pathways and their physiological roles.
• Fine Chemical Synthesis: Acts as a specialized building block for creating libraries of novel purine-based compounds for high-throughput screening.
• Reference Standard: Used as an analytical standard in quality control and method development for related active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3,7-Dihydro-1,3-Dipropyl-7-(2-Propynyl)-1H-Purine-2,6-Dione
CAS No.	102284-70-8
Molecular Formula	C16H22N4O2
Molecular Weight	302.37 g/mol
Synonyms	1,3-Dipropyl-7-(2-propynyl)-3,7-dihydro-1H-purine-2,6-dione; 7-(2-Propynyl)-1,3-dipropylxanthine; 1,3-Dipropyl-7-prop-2-ynylpurine-2,6-dione; PD 116,948; PD-116948; 1,3-Dipropyl-7-(prop-2-yn-1-yl)-1H-purine-2,6(3H,7H)-dione; Xanthine, 1,3-dipropyl-7-(2-propynyl)-
EINECS	Contact for details

Quality Control

Our 3,7-Dihydro-1,3-Dipropyl-7-(2-Propynyl)-1H-Purine-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.