Description

Imetit Dihydrobromide is a high-purity, selective histamine H3 receptor antagonist used extensively in pharmacological research. This compound is critical for studying the role of the histaminergic system in neurological and inflammatory processes. It is an essential tool for researchers and pharmaceutical developers in the fields of neuroscience, drug discovery, and receptor characterization. The product is supplied as Imetit Dihydrobromide CAS NO 102203-18-9, ensuring precise identification for global sourcing and regulatory documentation.

Application

• Pharmacological Research: A key reference standard and tool compound for studying histamine H3 receptor function and antagonism.
• Drug Discovery & Development: Used in high-throughput screening (HTS) and lead optimization programs targeting neurological disorders.
• Neuroscience Studies: Investigates the modulation of neurotransmitter release (e.g., acetylcholine, dopamine, norepinephrine) in the central nervous system.
• In Vitro & In Vivo Assays: Serves as a potent and selective antagonist in binding assays, functional cellular assays, and animal model studies.
• Biochemical Pathway Analysis: Helps elucidate the histaminergic pathways involved in wakefulness, cognition, appetite, and inflammation.
• Academic & Institutional Research: A fundamental reagent for universities and research institutes conducting basic science on G-protein coupled receptors (GPCRs).

Basic Information

Product Name	Imetit Dihydrobromide
CAS No.	102203-18-9
Molecular Formula	C9H15N3S · 2HBr
Molecular Weight	371.09 g/mol
Synonyms	Imetit dihydrobromide; SKF 100,398; 2-(1H-Imidazol-4-yl)ethyl (1-methyl-2-imidazolyl) sulfide dihydrobromide; 4-(2-((1-Methyl-1H-imidazol-2-yl)thio)ethyl)-1H-imidazole dihydrobromide; 1-Methyl-2-((2-(1H-imidazol-4-yl)ethyl)thio)imidazole dihydrobromide; Imetit (dihydrobromide); Imetit HBr; Histamine H3 receptor antagonist
EINECS	Contact for details

Quality Control

Our Imetit Dihydrobromide is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.