Description

2,4-Dimethoxy-N,n-Dimethyl-5-Iodo(122I)-Phenylisopropylamine is a specialized iodinated aromatic amine derivative, a key intermediate in the synthesis of radiopharmaceuticals and advanced organic compounds. Its value lies in its unique molecular architecture, which incorporates iodine-122, making it a critical precursor for positron emission tomography (PET) tracer development and research into neurological receptor ligands. This high-purity compound is essential for pharmaceutical R&D laboratories, radiochemistry facilities, and academic institutions focused on neuroimaging and diagnostic agent synthesis.

Application

• Radiopharmaceutical Precursor: Primary use as a building block for synthesizing iodine-122 labeled PET tracers targeting serotonin and other neurotransmitter systems.
• Neurological Research: Key intermediate in the development of ligands for studying brain receptors, aiding in the research of neurological disorders.
• PET Imaging Agent Synthesis: Utilized in the production of diagnostic imaging agents for oncology and cardiology applications.
• Organic Synthesis Intermediate: Serves as a versatile intermediate for introducing the dimethoxyiodophenylisopropylamine moiety into more complex molecules.
• Reference Standard: Used as a high-purity chemical reference standard in analytical method development and quality control for related APIs.
• Isotope Labeling Studies: Employed in metabolic pathway studies and pharmacokinetic research due to its radioactive iodine label.

Basic Information

Product Name	2,4-Dimethoxy-N,n-Dimethyl-5-Iodo(122I)-Phenylisopropylamine
CAS No.	102145-23-3
Molecular Formula	C13H20INO2
Molecular Weight	349.21 g/mol (for non-radioactive isotope I-127)
Synonyms	5-Iodo-2,4-dimethoxy-N,N-dimethylamphetamine; 2,4-Dimethoxy-5-iodo-N,N-dimethylamphetamine; 5-Iodo-DDD; 122I-Dimethoxyamphetamine derivative; 2,4-Dimethoxy-5-iodo-α-methylphenethylamine, N,N-dimethyl-; 5-Iodo-2,4-dimethoxy-N,N-dimethyl-1-phenyl-2-propanamine; Iodo-dimethoxy-DMA
EINECS	Contact for details

Quality Control

This high-value intermediate is manufactured under strict quality control protocols suitable for radiopharmaceutical research. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, radiochemical purity, and chemical purity. Certificates of Analysis (COA) are provided, detailing the specific activity, radionuclidic purity, and chemical specifications. Our processes align with cGMP principles where applicable for non-clinical research materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. Due to the radioactive component, store in accordance with all local and international regulations for handling radiochemicals. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0% (Chemical Purity)
Radiochemical Purity (TLC/HPLC)	≥ 98.0%
Specific Activity	Contact for details
Solubility	Soluble in common organic solvents (e.g., DMSO, Ethanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.