Description

Atractyloside Potassium Salt is a highly specific inhibitor of the mitochondrial adenine nucleotide translocator (ANT). This compound is a critical research tool for studying cellular energy metabolism, apoptosis, and mitochondrial function. It is primarily utilized by researchers and scientists in the fields of biochemistry, pharmacology, and molecular biology for mechanistic studies and assay development.

Application

• Biochemical Research: A key reagent for investigating mitochondrial permeability transition pore (MPTP) formation and the role of ANT in apoptosis.
• Pharmacology Studies: Used to screen and evaluate potential cardioprotective or neuroprotective agents that target mitochondrial dysfunction.
• Metabolic Pathway Analysis: Essential for elucidating the regulation of oxidative phosphorylation and ATP/ADP exchange across the inner mitochondrial membrane.
• Toxicology: Serves as a reference standard in studies of mitochondrial toxins and their mechanisms of action.
• Assay Development: Employed in the development and validation of high-throughput screening assays for mitochondrial targets.

Basic Information

Product Name	Atractyloside Potassium Salt
CAS No.	102130-43-8
Molecular Formula	C30H44KO16S2
Molecular Weight	763.90 g/mol
Synonyms	Atractyloside Dipotassium Salt; Potassium Atractyloside; Atractyloside K Salt; Atractyloside Acid Dipotassium Salt; NSC 107079; Gummiferin Potassium Salt; Atractyloside (potassium); Atractyloside dipotassium
EINECS	Contact for details

Quality Control

Our Atractyloside Potassium Salt is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Biological Activity	Inhibits mitochondrial ADP/ATP transport

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.