Description

15-Methyl-17-Phenyl-18,19,20-Trinorprostaglandin F2 Alpha Methyl Ester is a synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its structural specificity, enabling the study and synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of ophthalmic solutions, cardiovascular drugs, and other specialized medications. Our supply ensures high purity and batch-to-batch consistency critical for sensitive R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Research: Used in the development of glaucoma treatments, such as analogs of latanoprost or travoprost, to study intraocular pressure regulation.
• Cardiovascular Research: Employed in preclinical studies investigating vascular tone, platelet aggregation, and inflammatory responses.
• Biochemical Tool Compound: Serves as a precise agonist or antagonist in receptor binding assays and signal transduction pathway studies.
• Process Chemistry & Scale-Up: Supports route scouting, optimization, and pilot-scale manufacturing of prostaglandin derivatives.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	15-Methyl-17-Phenyl-18,19,20-Trinorprostaglandin F2 Alpha Methyl Ester
CAS No.	102130-27-8
Molecular Formula	C25H36O5
Molecular Weight	416.55 g/mol
Synonyms	15-Methyl-17-phenyl-18,19,20-trinor-PGF2α methyl ester; Methyl 15-methyl-17-phenyl-18,19,20-trinorprostaglandin F2α; 15(R/S)-Methyl-17-phenyl-18,19,20-trinorprostaglandin F2α methyl ester; 17-Phenyl-18,19,20-trinor-15-methyl PGF2α methyl ester; Prostaglandin F2α analog methyl ester; Latanoprost related compound; Travoprost intermediate; Isopropyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate (related structure)
EINECS	Contact for details

Quality Control

Our 15-Methyl-17-Phenyl-18,19,20-Trinorprostaglandin F2 Alpha Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the Certificate of Analysis. For long-term storage, consider storing under inert atmosphere at -20°C to maximize stability. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.