Description

4'-Methyl[1,1'-Biphenyl]-4-Sulfonyl Chloride is a specialized biphenyl sulfonyl chloride derivative, a crucial sulfonylation reagent and synthetic intermediate in advanced organic chemistry. Its core value lies in its reactivity as a sulfonyl chloride, enabling the efficient introduction of the sulfonyl group to construct complex molecules with high precision. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides that incorporate sulfonyl functional groups for enhanced activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a labeling reagent or activity-based probe to study protein function and interactions.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of specialized sulfonated dyes and colorants.
• Ligand & Catalyst Development: Precursor for creating chiral sulfonamide ligands used in asymmetric catalysis.

Basic Information

Product Name	4'-Methyl[1,1'-Biphenyl]-4-Sulfonyl Chloride
CAS No.	101366-51-2
Molecular Formula	C13H11ClO2S
Molecular Weight	266.74 g/mol
Synonyms	4'-Methylbiphenyl-4-sulfonyl chloride; [1,1'-Biphenyl]-4-sulfonyl chloride, 4'-methyl-; p-Tolylphenyl-4-sulfonyl chloride; 4-(4-Methylphenyl)benzenesulfonyl chloride; 4-Methyl-4'-sulfonylchlorobiphenyl; Biphenyl-4-sulfonyl chloride, 4'-methyl-; 4'-Methyl-1,1'-biphenyl-4-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4'-Methyl[1,1'-Biphenyl]-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting all critical quality parameters are available upon request to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.