Description

Aponeocarzinostatin is a potent enediyne antitumor antibiotic, a class of compounds known for their unique molecular architecture and significant biological activity. Its primary value lies in its role as a critical reference standard and research material for investigating novel cancer therapeutics and DNA-cleaving mechanisms. This product is essential for pharmaceutical R&D laboratories, academic institutions, and biotechnology companies focused on oncology drug discovery and molecular biology.

Application

• Pharmaceutical Reference Standard: Used as a high-purity benchmark for quality control and analytical method development in anticancer drug research.
• Biochemical Research: Serves as a key tool for studying the mechanism of action of enediyne antibiotics and their interaction with DNA.
• Oncology Drug Discovery: Acts as a lead compound or a structural template for the design and synthesis of new antitumor agents.
• Academic Studies: Utilized in university and institutional labs for investigating apoptosis, cell cycle arrest, and other cancer-related biological pathways.
• Biotechnology Applications: Employed in the development of antibody-drug conjugates (ADCs) or other targeted delivery systems for cancer treatment.

Basic Information

Product Name	Aponeocarzinostatin
CAS No.	101359-79-9
Molecular Formula	C35H48Cl3NO14
Molecular Weight	805.11 g/mol
Synonyms	Aponeocarzinostatin; Necoarzinostatin chromophore; NCS Chromophore; NCS-Chrom; Antibiotic NCS Chromophore; 101359-79-9; (1S,2R,3S,4S,5S,6R,7R,8S,9R,10R,11S,12R,13S,14R,15S,16R,17S,18R,19S,20R,21S,22R,23S,24S,25S,26R,27R,28S,29R,30R,31S,32R,33S,34R,35S)-35-(2-chloro-4,6-dihydroxy-3,5-dimethylbenzoyl)-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35-tetratriacontahydro-1,18-dihydroxy-8,15,22,29-tetramethyl-4,11,25,32-tetraoxo-19,26-epoxy-3,10,17,24,31-pentaoxa-2,9,16,23,30-pentaazapentatriacont-20-yn-1-yl 2,4,6-trideoxy-4-(dimethylamino)-3-C-methyl-3-O-methyl-α-L-lyxo-hexopyranoside
EINECS	Contact for details

Quality Control

Our Aponeocarzinostatin is manufactured and tested under strict quality management systems. Each batch is analyzed to ensure high purity and identity, with specifications typically meeting or exceeding research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (by IR and MS), and other relevant parameters is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.