Description

4-Methyl-2-Oxo-2H-1-Benzopyran-7-Yl-β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate is a key synthetic intermediate and reference standard in advanced organic and pharmaceutical chemistry. This compound is valued for its role as a protected glycoside derivative, crucial for the synthesis and analytical characterization of complex coumarin-based molecules. It is primarily required by research institutions and manufacturers in the pharmaceutical, nutraceutical, and fine chemical sectors for developing novel active ingredients and analytical methods.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel coumarin-derived drug candidates and active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used as a high-purity standard in HPLC, LC-MS, and NMR for quality control, method development, and impurity profiling in related compounds.
• Biochemical Research: Employed in studies of glycosidase enzymes, metabolic pathways, and the preparation of fluorescent or bioactive probes due to its coumarin fluorophore and sugar moiety.
• Fine Chemical Synthesis: A versatile precursor for generating more complex molecules through selective deprotection and further functionalization of the glucuronide and coumarin rings.
• Nutraceutical Development: Used in research for the synthesis of standardized, bioavailable forms of natural coumarin glycosides for health supplement formulations.

Basic Information

Product Name	4-Methyl-2-Oxo-2H-1-Benzopyran-7-Yl-β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate
CAS No.	101014-65-7
Molecular Formula	C25H26O14
Molecular Weight	550.47 g/mol
Synonyms	7-[(2,3,4-Tri-O-acetyl-β-D-glucopyranuronosyl)oxy]-4-methyl-2H-1-benzopyran-2-one methyl ester; Methyl (2,3,4-tri-O-acetyl-β-D-glucopyranuronosyl)-(1→7)-4-methylcoumarin; 4-Methylumbelliferyl-β-D-glucuronide triacetate methyl ester; 4-MU-β-D-Glucuronide triacetate methyl ester; 4-Methyl-7-β-D-glucuronosyloxycoumarin triacetate methyl ester; 7-Hydroxy-4-methylcoumarin β-D-glucuronide triacetate methyl ester; Hymecromone glucuronide triacetate methyl ester
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Oxo-2H-1-Benzopyran-7-Yl-β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.