Description

1,4-Dideoxy-1,4-Imino-L-Arabinitol Hcl is a high-purity iminosugar derivative, a potent and selective glycosidase inhibitor with significant biochemical and pharmacological research applications. Its core value lies in its ability to modulate carbohydrate-processing enzymes, making it a critical tool for studying metabolic pathways and developing therapeutic agents. This compound is essential for researchers and developers in the pharmaceutical, biotechnology, and life science sectors, particularly those focused on diabetes, viral infections, and lysosomal storage disorders.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of glycosidase inhibitor-based therapeutics.
• Biochemical Research: Used as a potent and selective inhibitor of α-glucosidase and other specific glycosidases in enzymatic studies and metabolic pathway analysis.
• Antiviral Agent Studies: Investigated for its potential activity against viruses like HIV and influenza by interfering with viral glycoprotein processing.
• Diabetes Research: Applied in studies targeting α-glucosidase for the management of type 2 diabetes and related metabolic syndromes.
• Glycobiology: A crucial tool for probing the structure and function of carbohydrates and their processing enzymes in cellular systems.
• Academic & Contract Research: Utilized in universities and CROs for fundamental research in chemistry, biochemistry, and molecular biology.

Basic Information

Product Name	1,4-Dideoxy-1,4-Imino-L-Arabinitol Hcl
CAS No.	100991-91-1
Molecular Formula	C5H12N2O2 • HCl
Molecular Weight	168.62 g/mol (Free base: 132.16 g/mol)
Synonyms	LABNA; DAB-1; 1,4-Dideoxy-1,4-imino-L-arabinitol hydrochloride; L-Arabinitol, 1,4-dideoxy-1,4-imino-, hydrochloride; (2R,3S,4R)-2-(Hydroxymethyl)piperidine-3,4-diol hydrochloride; 1,4-Dideoxy-1,4-imino-L-arabitol HCl; Isofagomine analog; Glycosidase inhibitor LABNA.
EINECS	Contact for details

Quality Control

Our 1,4-Dideoxy-1,4-Imino-L-Arabinitol Hcl is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. While produced to meet exacting internal standards, specifications can be aligned with specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.