Description

Atractyloside Sodium Salt is a high-purity biochemical compound widely utilized in life science research. Its primary value lies in its specific action as a potent inhibitor of the mitochondrial adenine nucleotide translocator (ANT), making it a critical tool for studying cellular energy metabolism and apoptosis. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors who require reliable, well-characterized reagents for mechanistic studies and assay development.

Application

• Biochemical Research: A key reagent for investigating mitochondrial function, ATP/ADP transport, and the regulation of the mitochondrial permeability transition pore (MPTP).
• Apoptosis Studies: Used to induce and study programmed cell death pathways linked to energy deprivation in various cell models.
• Pharmacology & Toxicology: Serves as a reference standard and tool compound for screening potential cardioprotective or neuroprotective agents that target mitochondrial dysfunction.
• Enzyme Inhibition Assays: Employed in in vitro assays to specifically inhibit the adenine nucleotide translocase, helping to elucidate its role in metabolic pathways.
• Academic & Industrial R&D: Fundamental for basic research in cell biology and for drug discovery programs focused on metabolic diseases, ischemia-reperfusion injury, and cancer.

Basic Information

Product Name	Atractyloside Sodium Salt
CAS No.	100938-11-2
Molecular Formula	C30H43NaO16S2
Molecular Weight	746.77 g/mol
Synonyms	Atractyloside Na Salt; Sodium Atractyloside; Atractyloside Sodium; NSC 107079; Atractyloside, sodium salt; Atractyloside (sodium); Atractyloside monosodium salt
EINECS	Contact for details

Quality Control

Our Atractyloside Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and moisture content. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccant and under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Biological Activity	Inhibits mitochondrial ADP/ATP transport

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.