Description

(+/-)-3-(2-Carboxypiperazin-4-Yl)-Propyl-1-Phosphonic Acid CAS NO 100828-16-8 is a high-purity, non-selective NMDA receptor antagonist used extensively in neuroscience research. This compound is critical for studying excitatory amino acid neurotransmission, glutamate receptor function, and neuroprotective mechanisms. It is an essential tool for pharmaceutical R&D teams, academic researchers, and diagnostic manufacturers focused on neurological disorders, stroke, and chronic pain pathways.

Application

• Neuroscience Research: A key pharmacological tool for studying NMDA receptor-mediated synaptic plasticity, excitotoxicity, and long-term potentiation (LTP).
• Pharmaceutical Development: Used in preclinical studies to model neurological conditions and screen potential neuroprotective agents for stroke, traumatic brain injury, and neurodegenerative diseases.
• Biochemical Assays: Serves as a standard and reference compound in receptor binding assays and functional studies of ionotropic glutamate receptors.
• Academic & Clinical Research: Facilitates investigations into the role of glutamate in chronic pain, epilepsy, and psychiatric disorders.

Basic Information

Product Name	(+/-)-3-(2-Carboxypiperazin-4-Yl)-Propyl-1-Phosphonic Acid
CAS No.	100828-16-8
Molecular Formula	C9H17N2O5P
Molecular Weight	264.22 g/mol
Synonyms	CPP; (±)-CPP; 3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid; CPPene (common name for related analog); NMDA receptor antagonist CPP; (RS)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid; 4-(3-Phosphonopropyl)piperazine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our (+/-)-3-(2-Carboxypiperazin-4-Yl)-Propyl-1-Phosphonic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity data, identity confirmation (IR, NMR), and impurity profiles. Our quality commitment aligns with standards for research chemicals and advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant use and storage under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.