Description

3-Hydroxy-19-Nor-1,3,5(10)-Cholatrien-24-Oic Acid is a high-purity, synthetic steroid derivative with a modified cholane skeleton, serving as a critical advanced intermediate in pharmaceutical research and development. Its structural specificity makes it invaluable for the synthesis of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease. This compound is essential for R&D chemists and process development scientists working on next-generation steroid-based pharmaceuticals and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroid-based drug candidates targeting hormone receptors.
• Research Chemical: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Process Development: Serves as a reference standard and starting material in the scale-up and optimization of synthetic routes for complex steroid molecules.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialized cholane derivatives for various high-value chemical applications.

Basic Information

Product Name	3-Hydroxy-19-Nor-1,3,5(10)-Cholatrien-24-Oic Acid
CAS No.	100772-18-7
Molecular Formula	C23H32O3
Molecular Weight	356.50 g/mol
Synonyms	19-Nor-3-hydroxy-1,3,5(10)-cholatrien-24-oic acid; 3-Hydroxy-19-norchola-1,3,5(10)-trien-24-oic acid; 19-Norcholatrienoic acid derivative; Norcholatriene carboxylic acid; Steroid intermediate 100772-18-7; Cholane derivative intermediate; 3-Hydroxy-19-nor-cholatrienic acid
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-19-Nor-1,3,5(10)-Cholatrien-24-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.