Description

2-(Bromomethyl)-6-Fluoropyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromomethyl and fluoro substituents on the pyridine ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to tag or modify biomolecules for diagnostic and research applications due to its reactive bromomethyl group.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-(Bromomethyl)-6-Fluoropyridine
CAS No.	100202-78-6
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	6-Fluoro-2-(bromomethyl)pyridine; 2-Bromomethyl-6-fluoropyridine; (6-Fluoropyridin-2-yl)methyl bromide; 6-Fluoro-2-pyridinemethyl bromide; 2-Fluoro-6-(bromomethyl)pyridine; α-Bromo-6-fluoro-2-picoline; Bromo(6-fluoro-2-pyridinyl)methane
EINECS	Contact for details

Quality Control

Our production of 2-(Bromomethyl)-6-Fluoropyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.