Description

3'-Trifluoromethylbiphenyl-4-Carbaldehyde is a high-purity, versatile biphenyl derivative featuring a trifluoromethyl group and an aldehyde functionality. This compound serves as a critical advanced pharmaceutical intermediate and a valuable building block in organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to develop novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for the development of advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The aldehyde group and aromatic halides (if present in derivatives) make it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research: Acts as a standard or reference compound in analytical method development and metabolic studies within chemical and pharmacological research.

Basic Information

Item	Detail
Product Name	3'-Trifluoromethylbiphenyl-4-Carbaldehyde
CAS No.	100036-64-4
Molecular Formula	C14H9F3O
Molecular Weight	250.22 g/mol
Synonyms	4-Formyl-3'-(trifluoromethyl)biphenyl; [1,1'-Biphenyl]-4-carboxaldehyde, 3'-(trifluoromethyl)-; 3'-(Trifluoromethyl)[1,1'-biphenyl]-4-carbaldehyde; 3'-Trifluoromethyl-4-biphenylcarboxaldehyde; 4-(3-(Trifluoromethyl)phenyl)benzaldehyde; 3'-Trifluoromethyl-4-formylbiphenyl
EINECS	Contact for details

Quality Control

Our 3'-Trifluoromethylbiphenyl-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.