Description

5'-Deoxypyridoxal 5'-Methylenephosphonic Acid is a chemically modified analog of vitamin B6, specifically designed as a potent and selective inhibitor of pyridoxal phosphate-dependent enzymes. This compound matters for researchers and developers in biochemistry and pharmacology, as it serves as a critical tool for studying enzyme mechanisms and metabolic pathways. It is primarily needed by professionals in pharmaceutical R&D, academic research institutions, and biotechnology companies focused on enzyme inhibition studies, metabolic disease research, and the development of novel therapeutic agents.

Application

• Biochemical Research: A key reagent for investigating the mechanisms of pyridoxal phosphate (PLP)-dependent enzymes, such as transaminases and decarboxylases.
• Enzyme Inhibition Studies: Used as a specific, active-site directed inhibitor to probe enzyme function and structure-activity relationships.
• Metabolic Pathway Analysis: Employed in cellular and molecular biology to dissect and understand vitamin B6-dependent metabolic networks.
• Pharmaceutical Development: Serves as a lead compound or reference standard in drug discovery programs targeting diseases involving PLP-enzyme dysregulation.
• Diagnostic Reagent Manufacturing: Potential use in the formulation of specialized diagnostic kits for clinical chemistry applications.

Basic Information

Product Name	5'-Deoxypyridoxal 5'-Methylenephosphonic Acid
CAS No.	19730-75-7
Molecular Formula	C9H12NO6P
Molecular Weight	261.17 g/mol
Synonyms	5'-Deoxypyridoxal Methylenephosphonate; PLP Inhibitor; Pyridoxal Phosphate Analog; 5'-Deoxy-PLP; Vitamin B6 Analog Inhibitor; 5'-Deoxypyridoxal Phosphonate; (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methylphosphonic Acid
EINECS	Contact for details

Quality Control

Our 5'-Deoxypyridoxal 5'-Methylenephosphonic Acid is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.