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Glycerol, [1,3-14C] CAS NO 19622-69-6
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CAS No.:19622-69-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Glycerol, [1,3-14C] is a carbon-14 labeled isotopologue of glycerol, a fundamental biochemical building block. This product is specifically designed for use as a radiolabeled tracer in metabolic and biochemical research, enabling precise tracking of glycerol's fate in complex biological systems. It is an essential tool for researchers in pharmaceutical development, lipid metabolism studies, and environmental science who require high-specific-activity, chemically pure tracers for sensitive detection methods.
Application
- Metabolic Pathway Tracing: Used to study the metabolism of triglycerides, phospholipids, and other glycerolipids in in vitro and in vivo systems.
- Pharmaceutical R&D: Employed in ADME (Absorption, Distribution, Metabolism, Excretion) studies for drug candidates that interact with lipid pathways.
- Biochemical Assays: Serves as a labeled substrate for enzymes such as glycerol kinase, lipases, and glycerol-3-phosphate dehydrogenase.
- Lipidomics Research: Facilitates the quantification and tracking of de novo lipid synthesis in cell culture and animal models.
- Environmental Science: Applied in studies investigating the biodegradation of glycerol-based compounds in various ecosystems.
Basic Information
| Product Name | Glycerol, [1,3-14C] |
| CAS No. | 19622-69-6 |
| Molecular Formula | C3H8O3 (with 14C at positions 1 and 3) |
| Molecular Weight | ~94.11 g/mol (exact mass depends on specific activity) |
| Synonyms | [1,3-14C]Glycerol; Glycerin-1,3-14C; 1,3-Labeled Glycerol-14C; 1,3-Di-14C-Glycerol; Glycerol-1,3-14C; 14C-Glycerol (1,3); Propane-1,2,3-triol-1,3-14C; Radiolabeled Glycerol |
| EINECS | Contact for details |
Quality Control
Every batch of our Glycerol, [1,3-14C] is manufactured and analyzed under strict quality systems to ensure radiochemical purity and chemical identity. Product specifications are verified by HPLC with radiometric detection and other appropriate analytical techniques. A comprehensive Certificate of Analysis (COA) detailing specific activity, radiochemical purity, chemical purity, and solvent composition is provided with each shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at 2-8°C. The product is light-sensitive and should be handled in accordance with standard laboratory safety protocols for radioactive materials. For long-term storage, keep frozen at -20°C or below.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow solution |
| Identification (IR / NMR) | Conforms to structure |
| Specific Activity | 50-60 mCi/mmol (Contact for exact value) |
| Radiochemical Purity (HPLC) | ≥ 97% |
| Chemical Purity (HPLC) | ≥ 98% |
| Concentration | 1.0 mCi/mL in ethanol:water (9:1) |
| Solvent Composition | Ethanol: Water (9:1 v/v) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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