Description

Hydrazine-1,2-Di(Sulfonyl Fluoride) is a specialized bifunctional sulfonyl fluoride reagent. This compound is highly valued for its role as a versatile chemical building block in advanced synthesis, enabling the introduction of sulfonyl fluoride groups which are key in modern click chemistry and covalent inhibitor development. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, chemical biology, and the development of novel covalent probes and PROTACs.

Application

• Medicinal Chemistry & Drug Discovery: Serves as a key intermediate for synthesizing covalent enzyme inhibitors and targeted protein degraders (PROTACs).
• Chemical Biology & Proteomics: Used as a probe for activity-based protein profiling (ABPP) to study enzyme function and identify novel drug targets.
• Click Chemistry: Acts as a bifunctional linker in SuFEx (Sulfur(VI) Fluoride Exchange) click chemistry for bioconjugation and polymer synthesis.
• Material Science: Employed in the surface functionalization of polymers and nanomaterials to introduce specific reactive handles.
• Agrochemical Research: Utilized in the synthesis of novel bioactive molecules with potential pesticidal or herbicidal activity.
• Academic Research: A critical reagent for developing new synthetic methodologies involving sulfonyl fluoride chemistry.

Basic Information

Item	Details
Product Name	Hydrazine-1,2-Di(Sulfonyl Fluoride)
CAS No.	19403-57-7
Molecular Formula	C2H4F2N2O4S2
Molecular Weight	246.19 g/mol
Synonyms	1,2-Hydrazinedisulfonyl difluoride; Hydrazine-1,2-disulfonyl difluoride; 1,2-Bis(fluorosulfonyl)hydrazine; Hydrazinebis(sulfonyl fluoride); Difluorohydrazinedisulfonate; N,N'-Difluorodisulfonylhydrazine; Bis(fluorosulfonyl)hydrazine; HDFS
EINECS	Contact for details

Quality Control

Our Hydrazine-1,2-Di(Sulfonyl Fluoride) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals, and custom purity grades or analytical data packages can be provided to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.