Description

Benzoyl Glucuronide is a crucial metabolite formed from the conjugation of benzoic acid with glucuronic acid. This compound is of significant importance in pharmaceutical research and development, particularly in the study of drug metabolism and pharmacokinetics. It serves as a key reference standard and analytical tool for scientists in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors who require high-purity materials for bioanalytical method development and validation.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for quantifying drug metabolites in biological matrices.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Essential for in vitro and in vivo studies to understand the metabolic pathways and clearance rates of drugs containing a benzoic acid moiety.
• Bioanalytical Method Development: Used to develop and validate sensitive HPLC-MS/MS or LC-MS methods for therapeutic drug monitoring and toxicology assessments.
• Enzyme Activity Assays: Employed as a substrate to study the activity of UDP-glucuronosyltransferase (UGT) enzymes.
• Toxicological Research: Investigation of metabolic detoxification pathways and the potential for drug-drug interactions.
• Academic Research: Used in university and institutional labs for fundamental research in biochemistry and medicinal chemistry.

Basic Information

Product Name	Benzoyl Glucuronide
CAS No.	19237-53-7
Molecular Formula	C₁₃H₁₄O₈
Molecular Weight	298.25 g/mol
Synonyms	Benzoyl-β-D-glucopyranosiduronic Acid; 1-O-Benzoyl-β-D-glucopyranuronic Acid; Benzoic Acid Glucuronide; β-D-Glucopyranosiduronic Acid, 1-O-Benzoyl-; Glucuronide, Benzoyl; Benzoyl-β-D-glucuronide; BZG
EINECS	Contact for details

Quality Control

Our Benzoyl Glucuronide is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. Certificates of Analysis (COA) detailing lot-specific results are available upon request, supporting compliance with internal quality standards and regulatory expectations for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.