Description

Pomalidomide CAS NO 19171-19-8 is a potent immunomodulatory and anti-angiogenic agent belonging to the class of thalidomide analogs. This compound is a critical active pharmaceutical ingredient (API) valued for its targeted mechanism of action in specific therapeutic areas. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of advanced oncology treatments.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of prescription medications for specific hematologic malignancies.
• Oncology Research: A key compound in preclinical and clinical research for studying immunomodulation, angiogenesis inhibition, and tumor microenvironment modulation.
• Drug Development: Serves as a reference standard and a building block in the synthesis of novel derivatives for new drug discovery programs.
• Clinical Trial Material (CTM): Supplied under GMP conditions for use in clinical trials investigating new treatment protocols or combination therapies.
• Biochemical Research: Used in vitro studies to investigate cereblon (CRBN)-dependent ubiquitination and degradation of specific protein substrates.

Basic Information

Product Name	Pomalidomide
CAS No.	19171-19-8
Molecular Formula	C13H11N3O4
Molecular Weight	273.24 g/mol
Synonyms	Pomalidomide; 4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; CC-4047; Actimid; Imnovid; Pomalyst; 3-Aminothalidomide; (RS)-3-Aminophthalimidoglutarimide
EINECS	Contact for details

Quality Control

Our Pomalidomide is manufactured and controlled under a strict quality management system. We provide material that meets high-purity standards suitable for pharmaceutical R&D and GMP applications. Comprehensive testing includes identity, assay, impurity profile, and residual solvents. A Certificate of Analysis (COA) documenting compliance with agreed specifications is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual unknown impurity: NMT 0.10% Total impurities: NMT 0.5%
Water (KF)	NMT 0.5%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.