Description

Imiquimod is a synthetic heterocyclic amine belonging to the imidazoquinoline family, recognized for its potent immunomodulatory activity. This compound is a critical active pharmaceutical ingredient (API) used in the formulation of topical medications. It is primarily utilized in the pharmaceutical industry for the development of dermatological treatments. Imiquimod CAS NO 99011-02-6 is essential for manufacturers requiring a high-purity, reliable ingredient for advanced therapeutic applications.

Application

• Topical Antiviral/Antineoplastic Formulations: Primary API in prescription creams for the treatment of external genital and perianal warts (condylomata acuminata).
• Actinic Keratosis Therapy: Key component in topical treatments for pre-cancerous skin lesions caused by sun damage.
• Superficial Basal Cell Carcinoma (sBCC) Treatment: Used in non-surgical, topical immunotherapy for certain types of non-melanoma skin cancer.
• Dermatological Research: Serves as a toll-like receptor 7 (TLR7) agonist in immunological and oncological research studies.
• Pharmaceutical Intermediates: Acts as a starting material or intermediate in the synthesis of more complex immunomodulatory compounds.
• Veterinary Medicine: Investigated for use in topical treatments for certain cutaneous conditions in animals.

Basic Information

Product Name	Imiquimod
CAS No.	99011-02-6
Molecular Formula	C14H16N4
Molecular Weight	240.31 g/mol
Synonyms	1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; R-837; S-26308; Aldara (brand name ingredient); Imiquimodum; IQM
EINECS	Contact for details

Quality Control

Our Imiquimod is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as assay, related substances, residual solvents, and microbiological quality. We adhere to cGMP guidelines to ensure consistency, purity, and traceability for our B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%
Microbiological Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.