Description

1,1,1-Trifluoro-6-Phenylhex-5-(E)-Ene-2,4-Dione is a specialized fluorinated diketone building block with a conjugated enone system. This compound is valued for its unique reactivity profile, serving as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for chemists and R&D teams in fine chemical, pharmaceutical, and material science industries seeking to introduce trifluoromethyl and β-diketone functionalities into target structures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and fluorinated materials with unique thermal and chemical resistance.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chelating ligands and catalysts for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and the properties of fluoroorganic compounds.
• Dye and Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	1,1,1-Trifluoro-6-Phenylhex-5-(E)-Ene-2,4-Dione
CAS No.	18931-64-1
Molecular Formula	C12H9F3O2
Molecular Weight	242.19 g/mol
Synonyms	6-Phenyl-1,1,1-trifluorohex-5-ene-2,4-dione; (E)-1,1,1-Trifluoro-6-phenylhex-5-ene-2,4-dione; 3-Benzylidene-1,1,1-trifluoropentane-2,4-dione; 3-(Phenylmethylene)-1,1,1-trifluoro-2,4-pentanedione; 1,1,1-Trifluoro-6-phenyl-5-hexene-2,4-dione; Trifluoromethylated β-diketone; TFPHED
EINECS	Contact for details

Quality Control

Our 1,1,1-Trifluoro-6-Phenylhex-5-(E)-Ene-2,4-Dione is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. Our quality system supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents. For long-term storage, consider using an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.