Description

D-Fructose-Ul-14C is a uniformly carbon-14 labeled isotopologue of D-fructose, a fundamental monosaccharide. This radiolabeled compound is essential for advanced metabolic and pharmacokinetic studies, providing researchers with a precise tracer to elucidate biochemical pathways. It is a critical tool for scientists in pharmaceutical R&D, agricultural chemistry, and nutritional science who require high-specific-activity materials for autoradiography, LC-MS, and other sophisticated analytical techniques.

Application

• Metabolic Pathway Tracing: Used in in vitro and in vivo studies to map the absorption, distribution, metabolism, and excretion (ADME) of fructose and related compounds.
• Pharmaceutical Research: Critical for drug metabolism studies (DMPK) to understand how therapeutic agents interact with sugar metabolism pathways.
• Nutritional Science: Enables detailed investigation into fructose metabolism, liver function, and the biochemical basis of dietary-related health conditions.
• Agricultural Biochemistry: Applied in plant physiology research to study carbohydrate synthesis, transport, and utilization in crops.
• Enzymology Studies: Serves as a substrate for kinetic studies of enzymes like ketohexokinase and fructokinase.
• Biomarker Development: Aids in the development and validation of analytical methods (e.g., LC-MS/MS) for detecting fructose-derived metabolites in complex biological matrices.

Basic Information

Product Name	D-Fructose-Ul-14C
CAS No.	18875-34-8
Molecular Formula	C6H12O6 (uniformly labeled with 14C)
Molecular Weight	Contact for details (varies with specific activity)
Synonyms	D-(-)-Fructose-UL-14C; Fructose (U-14C); Levulose-UL-14C; Fruit Sugar-UL-14C; (3S,4R,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one-UL-14C; β-D-Fructopyranose-UL-14C; β-D-Fructofuranose-UL-14C; [UL-14C]-Fructose
EINECS	Contact for details

Quality Control

Every batch of D-Fructose-Ul-14C is manufactured and analyzed under strict quality systems to ensure identity, purity, and specific activity. Our products undergo rigorous quality testing, including radiochemical purity analysis by HPLC and TLC, to ensure compliance with the high standards required for research use. Certificates of Analysis (COA), detailing specific activity, purity, and analytical methods, are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C or as specified on the label or Certificate of Analysis. This product is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric moisture. For long-term storage, consider conditions recommended for radiolabeled compounds.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC, TLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Specific Activity	Customer specified (mCi/mmol)
Solvent (if supplied in solution)	Specified on COA (e.g., Water, Ethanol)
Concentration (if supplied in solution)	Specified on COA (mCi/mL, μCi/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.