Description

Benzene, 1-Fluoro-4-(1-Propyn-1-Yl)- is a specialized fluorinated aromatic building block with a terminal alkyne functional group, offering versatile reactivity for advanced organic synthesis. This compound is valued for its role in creating complex molecular architectures, particularly in the development of pharmaceuticals and advanced materials. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated aromatic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging Sonogashira and other cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where the fluorine atom and alkyne group enhance biological activity and stability.
• Material Science: Serves as a monomer or precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in academic and industrial laboratories for developing new synthetic methodologies, particularly in palladium-catalyzed coupling reactions.
• Fluorine Chemistry: A valuable substrate for studying structure-activity relationships (SAR) and introducing fluorine into complex organic molecules to modulate their physicochemical properties.

Basic Information

Product Name	Benzene, 1-Fluoro-4-(1-Propyn-1-Yl)-
CAS No.	18826-59-0
Molecular Formula	C9H7F
Molecular Weight	134.15 g/mol
Synonyms	1-Fluoro-4-(prop-1-yn-1-yl)benzene; 4-Fluorophenylacetylene; p-Fluorophenylacetylene; 1-Ethynyl-4-fluorobenzene; 4-Ethynylfluorobenzene; (4-Fluorophenyl)ethyne; 4-Fluoroethynylbenzene; 4-Fluorobenzeneacetylene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for parameters such as assay (by GC or HPLC), identity (by FT-IR or NMR), and impurity profile are available upon request. We adhere to strict internal quality management protocols to ensure supply reliability and product integrity for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are sealed when not in use and stored away from heat sources and open flame. Keep under an inert atmosphere such as nitrogen for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.