Description

8-Quinolinesulfonyl Chloride is a versatile and reactive organosulfur compound widely used as a key synthetic intermediate. Its primary value lies in its sulfonyl chloride functional group, which readily undergoes nucleophilic substitution reactions to form sulfonamides and sulfonate esters. This makes it an essential building block for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those containing sulfonamide moieties with potential biological activity.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the quinoline-sulfonyl scaffold imparts specific activity.
• Dye and Pigment Manufacturing: Serves as an intermediate for creating specialized sulfonated dyes and colorants.
• Material Science Research: Employed in the development of functional polymers, ligands for metal complexes, and advanced organic materials.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules due to its reactivity with amines and alcohols.
• Fine Chemical Production: Acts as a building block for various specialty chemicals used in catalysis and organic synthesis.

Basic Information

Product Name	8-Quinolinesulfonyl Chloride
CAS No.	18704-37-5
Molecular Formula	C9H6ClNO2S
Molecular Weight	227.67 g/mol
Synonyms	Quinoline-8-sulfonyl chloride; 8-Sulfonylchloroquinoline; 8-Quinolylsulfonyl chloride; 8-Quinolinesulfonic acid chloride; 1-Azanaphthalene-8-sulfonyl chloride; NSC 403697; 8-Quinoline sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 8-Quinolinesulfonyl Chloride is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere such as nitrogen or argon to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.