Description

2-Fluoro-5-Nitro-6-Picoline is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both fluorine and nitro substituents on the pyridine ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for designing molecular probes and tags due to its reactive nitro group, which can be further functionalized.

Basic Information

Product Name	2-Fluoro-5-Nitro-6-Picoline
CAS No.	18605-16-8
Molecular Formula	C6H5FN2O2
Molecular Weight	156.12 g/mol
Synonyms	2-Fluoro-5-nitro-6-methylpyridine; 6-Methyl-2-fluoro-5-nitropyridine; 5-Nitro-2-fluoro-6-picoline; 2-Fluoro-5-nitro-6-methylpyridine; 18605-16-8; 2-Fluoro-5-nitro-6-methyl-pyridine; 5-Nitro-2-fluoro-6-methylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Nitro-6-Picoline is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.