Description

Pyrimidine, 4,6-Difluoro-2-Methyl- (8Ci,9Ci) is a high-purity, fluorinated heterocyclic building block essential for advanced organic synthesis. Its core value lies in its role as a key intermediate for creating complex molecules with tailored biological and physical properties. This compound is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials. We supply it globally with a focus on consistent quality and reliable supply chain integrity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated pyrimidine core.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its stable heterocyclic structure.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and labeled compounds for biochemical research.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse client projects.

Basic Information

Product Name	Pyrimidine, 4,6-Difluoro-2-Methyl- (8Ci,9Ci)
CAS No.	18382-80-4
Molecular Formula	C5H4F2N2
Molecular Weight	130.10 g/mol
Synonyms	4,6-Difluoro-2-methylpyrimidine; 2-Methyl-4,6-difluoropyrimidine; 4,6-Difluoro-2-methyl-1,3-diazine; 2-Methyl-4,6-difluoro-1,3-diazine; Difluoromethylpyrimidine; NSC 523796; AI3-52231
EINECS	Contact for details

Quality Control

Every batch of 4,6-Difluoro-2-methylpyrimidine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.