Description

Clorgyline is a potent, selective, and irreversible inhibitor of monoamine oxidase A (MAO-A), a key enzyme in neurotransmitter metabolism. This compound is a critical research tool in neuroscience and pharmacology for studying the role of MAO-A in neurological function and behavior. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and chemical suppliers serving the life sciences sector for investigative and development purposes.

Application

• Neuroscience Research: A fundamental tool for investigating the physiological and behavioral roles of monoamine oxidase A (MAO-A) in the central nervous system.
• Pharmacological Studies: Used in in vitro and in vivo models to study neurotransmitter dynamics, particularly serotonin, norepinephrine, and dopamine.
• Biochemical Assay Development: Serves as a reference standard and active control in enzymatic assays designed to screen for MAO-A inhibitory activity.
• Psychiatric Disorder Research: Employed in preclinical research models related to depression, anxiety, and other mood disorders where MAO-A dysregulation is implicated.
• Chemical Intermediate: Can be used in the synthesis of more complex molecules for specialized research applications.
• Reference Standard: Provides a high-purity benchmark for analytical methods, including HPLC and LC-MS, in quality control and metabolic studies.

Basic Information

Product Name	Clorgyline
CAS No.	17780-72-2
Molecular Formula	C11H13ClN2
Molecular Weight	208.69 g/mol
Synonyms	N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride; (2,4-Dichlorophenoxy)propyl-methyl-prop-2-yn-1-amine; Chlorgilin; Chlorgyline; Clorgilin; Clorgyline HCl; ECN 217-096-4; Pargyline analog
EINECS	Contact for details

Quality Control

Our Clorgyline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation (IR, NMR), purity assessment (HPLC), and residual solvent analysis to ensure it meets exacting research-grade standards. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.